Factores de riesgo de artrosis de rodilla, cadera o ambas en mujeres chilenas de mediana edad: un estudio de cohorte de tres décadas / Risk factors for the development of osteoarthritis in middle-aged women

BACKGROUND: Osteoarthritis (OA) is a health problem affecting millions of individuals worldwide. Aim: To evaluate risk factors for hip and knee osteoarthritis (OA) in women aged 40 to 59 years. MATERIAL AND METHODS: Analysis of a prospective cohort of 1159 women attending preventive health care programs and followed during 28 years. They underwent a clinical and laboratory evaluation from 1990 to 1993. The diagnosis of OA was retrieved from registries of a special program for osteoarthritis in 2020. RESULTS: Twenty four percent of participants developed osteoarthritis during the follow-up. At the beginning of the study and compared with women without OA, they were older (median [interquartile range or IQR]: 49.6 [8.5] and 47.2 [8.2] years respectively), had a higher body mass index (26.3 [5.3] and 25.1 [5.3] respectively), and a higher frequency of jobs with low qualification (76 and 62% respectively). The presence of type 2 diabetes mellitus, chronic hypertension, a previous history of alcohol or cigarette consumption, postmenopausal status and lipid and glucose blood levels did not differ between women with or without OA. Cox regression showed a final model that incorporates body mass index (hazard ratio (HR): 1.04; 95% confidence intervals (CI): 1.01-1.07), age (HR: 1.05; 95% CI: 1.03-1.08) and having an unqualified job (HR: 1.88; 95% CI: 1.43-2.47) as risk factors for OA. CONCLUSIONS: Obesity and the type of job are the most relevant risk factors found for OD: both may be modified with proper care.

Evolución epidemiológica de la artroplastia de cadera y rodilla durante 17 años en pacientes con artrosis severa en un hospital Chileno / Evolution of hip and knee arthroplasty epidemiology in a single hospital of Chile: a 17 years overview

INTRODUCCIÓN: La artroplastia total de cadera (ATC), es la cirugía del siglo XX por el impacto en la calidad de vida. Por su parte, la artroplastia de rodilla (AR), ha demostrado ser un procedimiento costo-efectivo en gonartrosis. OBJETIVO: Describir la evolución de ATC y AR, en cuanto a número de procedimientos, edad y género en pacientes operados en un hospital general. MÉTODO: Estudio transversal analítico. Fueron incluidos todos los procedimientos realizados en un único centro, entre enero de 2002 y diciembre 2018, que estuvieran registrados por los códigos de prestación Fonasa 2104129 y 2104153. Fueron excluidos todos los procedimientos de revisión de artroplastia, tumores y fracturas. Se realizó un análisis de correlación de Spearman, se estableció una significancia de 0,05. RESULTADOS: Fueron incluidos 3270 procedimientos, 1975 corresponden a ATC (60,4%) y 1295 AR (39,6%). El número de ATC ha ido aumentando, en 2002 fueron realizados 122, mientras que en 2018, fueron 164. Por su parte, las AR también aumentaron, en 2002 fueron realizadas 40, mientras que en 2018 fueron 155. La proporción ATC/AR ha disminuido significativamente. La edad promedio ha disminuido en AR y aumentado en ATC, sin significación estadística. En ATC, se observa un incremento en la proporción de hombres operados. CONCLUSIONES: El perfil epidemiológico de los pacientes operados de artroplastia ha cambiado significativamente. La epidemiología mundial y la de este estudio muestran un significativo incremento de pacientes que requieren AR, por lo cual, parece importante incluir ese procedimiento en las necesidades sanitarias a satisfacer, en el diseño de nuevas políticas públicas.

OBJECTIVE: To describe the evolution of hip and knee arthroplasty in a general hospital, in terms of number of procedures, average age and gender. METHOD: Analytical cross-sectional study. All procedures performed between January 2002 and December 2018 in a single center were included. All procedures performed for revision surgery, tumors or fracture were excluded. The following data were obtained from the registry: age at the time of surgery, gender of the patient and year of the procedure. A Spearman correlation analysis was performed, a significance of 0.05 was established. RESULTS: 3270 procedures were included, 1975 correspond to hip arthroplasty (60.4%) and 1295 to knee arthroplasty (39.6%). The number of hip arthroplasty has increased over time, in 2002 a total of 122 procedures were performed and in 2018 there were 164. On the other hand, knee arthroplasty procedures have also increased, from 40 in 2002 to 155 in 2018. The ratio between hip and knee arthroplasty has been decreasing, this finding being significant. The average age has been decreasing in knee arthroplasty, meanwhile, decreasing in hip arthroplasty during the studied period. On the other hand, the proportion of men that underwent hip arthroplasty has been increasing over time. CONCLUSIONS: The number of knee arthroplasty has increased significantly, decreasing its difference with respect to the number of hip arthroplasty. An explosive increase in knee arthroplasty has been described in the literature, consistent with the outcomes of this study, so it seems important to include this procedure the new health public policies.

Tendencia temporal y evaluación demográfica de hospitalizaciones por osteoartritis / Temporal trends and demographic evaluation of hospitalizations due to osteoarthritis

OBJETIVO: Describir la tendencia temporal de osteoartritis (OA) según egresos hospitalarios considerando ubicación anatómica, distribución por sexo, edad, condiciones más frecuentes, y ubicación geográfica en Chile entre los años 2012 y 2018. METODOLOGÍA: Estudio descriptivo, retrospectivo, poblacional, que analizó las bases de datos públicas del Departamento de Estadísticas e Información en Salud (DEIS) del Ministerio de Salud de Chile, en particular los registros con codificación de M15 a M19. Se calcularon las tasas por 100 mil egresos hospitalarios, así como también el porcentaje de OA según las categorías analizadas. RESULTADOS: Se encontraron 11.622.605 egresos hospitalarios entre 2012 y 2018. El número total de egresos hospitalarios por OA fue de 78.700. Se observó que la distribución por sexo fue similar a lo largo de los años ( 40% y 60% en hombres y mujeres, respectivamente). El rango de edad más afectado fue el de 65 a 79 años, cuya tasa promedio fue de 2.046 por 100 mil egresos; además, fue el grupo que presentó el mayor aumento (60%) en su tasa de 2012 a 2018. La Región Metropolitana (291,7 egresos) y de Valparaíso (89,6 egresos) presentaron las tasas más altas. La cadera (56,6%) y la rodilla (31%) fueron las ubicaciones más frecuentes de casos de OA, con distribución similar por sexo, edad y geografía en comparación a los egresos totales por OA. CONCLUSIONES: Los egresos hospitalarios por OA en Chile aumentaron entre 2012 y 2018, preferencialmente en casos de OA en las articulaciones de cadera y rodilla en el grupo de mujeres de edad avanzada de la zona centro del país. NIVEL DE EVIDENCIA: Estudio descriptivo.

OBJECTIVE: To describe the temporal trends of osteoathritis (OA) according to hospital discharges considering anatomical location, distribution by gender, age, more frequent conditions, and geographic location in Chile between 2012 and 2018. METHODOLOGY: A retrospective, descriptive and population study which analyzed the public databases of the Department of Health Statistics and Information (Departamento de Estadísticas e Información en Salud, DEIS, in Spanish) of the Ministry of Health of Chile, in particular the records with codes M15 through M19. Rates per 100 thousand hospital discharges were calculated, as well as the percentage of OA according to the categories analyzed. RESULTS: A total of 11,622,605 hospital discharges were found between 2012 and 2018. The total number of hospital discharges due to OA was of 78,700. The distribution by gender was similar over the years ( 40% and 60% among men and women respectively). Adults aged between 65 and 79 years were the most affected, and their average rate was of 2,046 per 100 thousand discharges. It was also the group that presented the highest increase (60%) in rate from 2012 to 2018. The Metropolitan Region (291.7 discharges) and Valparaíso (89.6 discharges) presented the highest rates in Chile. The hip (56.6%) and knee (31%) were the most frequent locations of OA, which presented similar distribution by gender, age and geography when compared with the total discharges due to OA. CONCLUSIONS: Hospital discharges due to OA in Chile increased between 2012 and 2018, preferentially in cases of hip and knee-joint OA in the group of elderly women in the central area of the country. LEVEL OF EVIDENCE: Descriptive study.

Prevalence of joint pain and osteoarthritis in obese brazilian population / Prevalência de dor articular e osteoartrite na população obesa brasileira

ABSTRACT Background: High body mass index, as well as maintaining this condition for a long period of time, are important risk factors for the development of osteoarthritis. Aim: To determine joint pain and osteoarthritis prevalence in patients referred to bariatric surgery. Methods: Morbidly obese patients referred to bariatric surgery responded to the visual analogue pain scale (VAS) and the WOMAC questionnaire. X-rays of the hips and knees were evaluated. The primary endpoints were self-reported joint pain and the diagnosis of osteoarthritis by clinical and radiological criteria of the American College of Rheumatology. Results: 141 patients were interviewed (85.1% women) with a mean age of 40 years. The mean body mass index was 46. The lumbar spine and knee joint were the most commonly reported as painful (77.9% and 73.2% respectively). Prevalence of knee osteoarthritis was 63.1% and hip osteoarthritis was 40.8%. Age, mean VAS and WOMAC scores were higher in the osteoarthritic individuals. Conclusion: There is prevalence of 90.1% of pain symptoms in morbidly obese patients referred to bariatric surgery. The prevalence of knee osteoarthritis was 63.1% and hip osteoarthritis was 40.8% in this sample.

RESUMO Racional: Alto índice de massa corpórea, assim como a manutenção desta condição por longo período de tempo, são importantes fatores de risco para o desenvolvimento de osteoartrite. Objetivo: Determinar a prevalência de dor articular e osteoartrite em pacientes aguardando cirurgia bariátrica. Métodos: Pacientes obesos mórbidos responderam à escala e questionário (VAS e WOMAC) de dor e função. Radiografias dos quadris e joelhos foram avaliadas. Os desfechos primários foram dor articular referida nos questionários e o diagnóstico de osteoartrite feito através dos critérios clinicoradiológicos do Colégio Americano de Reumatologia. Resultados: Cento e quarenta e um pacientes foram entrevistados (85,1% mulheres) com idade média de 40 anos. A média do índice de massa corpórea foi de 46. Coluna lombar e joelhos foram as regiões mais comumente referidas com dor (77,9% e 73,2% respectivamente). A prevalência de osteoartrite dos joelhos foi de 63,1% e dos quadris foi de 40,8%. Idade, média da escala visual de dor e resultados do questionário de WOMAC foram maiores nos indivíduos com osteoartrite. Conclusão: Há prevalência de 90,1% de sintomas dolorosos nos pacientes obesos mórbidos encaminhados para cirurgia bariátrica. A osteoartrite dos joelhos foi de 63,1% e de quadris de 40,8%.

Prevalence of osteoarthritis of weight bearing joints in relation to body weight in both genders

Obesity is an important and increasing public health problem, being a risk factor for overall mortality and major chronic disease. To determine relationship between different measures of body mass index and incidence of hip and knee osteoarthritis in male and female. Comparison of prevalence of primary osteoarthritis of knee and hip. Between age and sex matched control from outpatient clinic of Erbil and Rizgary teaching hospital over period of eleven months starting on Jan 2007.this constituted one hundred and eighty five subjects of normal body `mass index. And one hundred and sixty subjects with high body mass index. Subjects fulfilling our inclusion criteria underwent clinical evaluation and radiology of their knee and hip joints, we assessed by chi-squared test, differences in frequency of osteoarthritis between those with normal body mass index and those with high body mass index and between male and female Obesity was a stronger predictor of osteoarthritis of knee joint with no sex and age difference. In the prevalence of osteoarthritis of hip joint. No link between obesity and hip osteoarthritis was found in this study. Obesity in 35-45 year old men and female will predispose to primary osteoarthritis of the knee

Relationship between the sphericity of femoral head-acetabulum and the low incidence of primary osteoarthritis of the hip joint in Koreans

I examined the sphericity and the congruity of the femoral head and the acetabulum in 172 Korean fetuses and in 655 Korean adults. I found that Korean fetal acetabuli and femoral heads are spherical and that the proportion of the head contained in the acetabulum remains constant and congruous throughout the fetal life. Adult actabuli and femoral heads are also spherical in both gender and are there are no visible changes in the shape of the acetabuli and the femoral heads with respect to age. No evidence was found that the congruity of the hip joint is a cause of osteoarthritis of the hip joint. Clinical Relevance: Stable hip joints at the time of birth provide an explantation for the low incidence of congenital dislocation of the hip joint in Koreans. The spherical femoral head and acetabulum (congruous hip joint) seem to be a contributing factor to the low incidence of primary osteoarthritis of the hip in Koreans.

Relationship between the sphericity of femoral head-acetabulum and the low incidence of primary osteoarthritis of the hip joint in Koreans

I examined the sphericity and the congruity of the femoral head and the acetabulum in 172 Korean fetuses and in 655 Korean adults. I found that Korean fetal acetabuli and femoral heads are spherical and that the proportion of the head contained in the acetabulum remains constant and congruous throughout the fetal life. Adult actabuli and femoral heads are also spherical in both gender and are there are no visible changes in the shape of the acetabuli and the femoral heads with respect to age. No evidence was found that the congruity of the hip joint is a cause of osteoarthritis of the hip joint. Clinical Relevance: Stable hip joints at the time of birth provide an explantation for the low incidence of congenital dislocation of the hip joint in Koreans. The spherical femoral head and acetabulum (congruous hip joint) seem to be a contributing factor to the low incidence of primary osteoarthritis of the hip in Koreans.